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For a child with symptoms of perianal itching and a positive cellophane tape test, which medication is most appropriate?

  1. Avermectin

  2. Bebendazole

  3. CMetronidazole

  4. DPermethrin cream

The correct answer is: Bebendazole

The most appropriate medication for a child with symptoms of perianal itching and a positive cellophane tape test is benbendazole. The presence of perianal itching, along with a positive tape test, suggests an infection with pinworms (Enterobius vermicularis). Benbendazole is effective in treating pinworm infections as it works by interfering with the worm's ability to absorb glucose, leading to its death. This medication is typically the first-line treatment for enterobiasis, particularly in pediatric patients, due to its safety profile and efficacy. Additionally, it is often given to the household members as a prophylactic measure since pinworm infections are highly contagious. Other options, while used for different parasitic infections or conditions, are not the first-line choice for treating pinworm infections. Avermectin is generally utilized for stronger parasitic infections but is not indicated specifically for pinworms. Metronidazole is effective against protozoan infections and anaerobic bacteria, thus not suitable for this particular case. Permethrin cream is used primarily for scabies and lice but does not target pinworms directly.